Transcriptomic Profiling of the Allorecognition Response to Grafting in the Demosponge Amphimedon queenslandica
Sponges, despite their simple body plan, discriminate between self and nonself with remarkable specificity.Sponge grafting experiments simulate the effects of natural self or nonself contact under laboratory conditions.Here we take a transcriptomic approach to investigate the temporal response to self and nonself grafts in the marine demosponge Amp